groL-2 protein (Bradyrhizobiaceae bacterium SG6C)

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groL-2

Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (547 aa)

Predicted Functional Partners:

groS-2

0.997

groS

0.995

dnaK

0.994

CSIRO_4236

0.982

grpE

0.978

dnaJ

0.930

cbpA

0.925

CSIRO_2812

0.900

CSIRO_1825

0.899

hrpB

0.855

Your Current Organism:

Bradyrhizobiaceae bacterium SG6C

NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSIRO_1825	CSIRO_4236	CSIRO_1825	CSIRO_4236	DnaJ-like molecular chaperone.	Hypothetical protein.	0.931
CSIRO_1825	dnaK	CSIRO_1825	CSIRO_0890	DnaJ-like molecular chaperone.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.994
CSIRO_1825	groL-2	CSIRO_1825	CSIRO_3626	DnaJ-like molecular chaperone.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.899
CSIRO_1825	groS	CSIRO_1825	CSIRO_0457	DnaJ-like molecular chaperone.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.612
CSIRO_1825	groS-2	CSIRO_1825	CSIRO_3625	DnaJ-like molecular chaperone.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.622
CSIRO_1825	grpE	CSIRO_1825	CSIRO_0892	DnaJ-like molecular chaperone.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.950
CSIRO_1825	hrpB	CSIRO_1825	CSIRO_0560	DnaJ-like molecular chaperone.	ATP-dependent helicase HrpB.	0.668
CSIRO_2812	dnaK	CSIRO_2812	CSIRO_0890	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.831
CSIRO_2812	groL-2	CSIRO_2812	CSIRO_3626	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.900
CSIRO_4236	CSIRO_1825	CSIRO_4236	CSIRO_1825	Hypothetical protein.	DnaJ-like molecular chaperone.	0.931
CSIRO_4236	cbpA	CSIRO_4236	CSIRO_4192	Hypothetical protein.	DnaJ-class molecular chaperone CbpA.	0.931
CSIRO_4236	dnaJ	CSIRO_4236	CSIRO_0889	Hypothetical protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.931
CSIRO_4236	dnaK	CSIRO_4236	CSIRO_0890	Hypothetical protein.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.996
CSIRO_4236	groL-2	CSIRO_4236	CSIRO_3626	Hypothetical protein.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.982
CSIRO_4236	groS	CSIRO_4236	CSIRO_0457	Hypothetical protein.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.807
CSIRO_4236	groS-2	CSIRO_4236	CSIRO_3625	Hypothetical protein.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.807
CSIRO_4236	grpE	CSIRO_4236	CSIRO_0892	Hypothetical protein.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.844
cbpA	CSIRO_4236	CSIRO_4192	CSIRO_4236	DnaJ-class molecular chaperone CbpA.	Hypothetical protein.	0.931
cbpA	dnaK	CSIRO_4192	CSIRO_0890	DnaJ-class molecular chaperone CbpA.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.996
cbpA	groL-2	CSIRO_4192	CSIRO_3626	DnaJ-class molecular chaperone CbpA.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.925

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