Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSIRO_3681Low-specificity L-threonine aldolase. (362 aa)    
Predicted Functional Partners:
gcvP
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.901
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.874
CSIRO_1325
Threonine synthase.
    
 0.835
CSIRO_3820
Threonine dehydratase.
   
 
 0.835
CSIRO_3945
Serine--glyoxylate aminotransferase.
    
 0.796
CSIRO_1343
5-aminolevulinate synthase.
     
 0.786
thiO
Glycine oxidase ThiO.
     
 0.703
CSIRO_1560
Electron transfer flavoprotein alpha subunit.
    
  0.702
CSIRO_1055
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.696
rnr
3'-to-5' exoribonuclease RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
     
  0.684
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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