| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_0671 | CSIRO_1512 | CSIRO_0671 | CSIRO_1512 | Aspartokinase; Belongs to the aspartokinase family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.636 |
| CSIRO_0671 | CSIRO_3855 | CSIRO_0671 | CSIRO_3855 | Aspartokinase; Belongs to the aspartokinase family. | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | 0.462 |
| CSIRO_0671 | CSIRO_3858 | CSIRO_0671 | CSIRO_3858 | Aspartokinase; Belongs to the aspartokinase family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.777 |
| CSIRO_1512 | CSIRO_0671 | CSIRO_1512 | CSIRO_0671 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Aspartokinase; Belongs to the aspartokinase family. | 0.636 |
| CSIRO_1512 | CSIRO_2169 | CSIRO_1512 | CSIRO_2169 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| CSIRO_1512 | CSIRO_3304 | CSIRO_1512 | CSIRO_3304 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.961 |
| CSIRO_1512 | CSIRO_3858 | CSIRO_1512 | CSIRO_3858 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.848 |
| CSIRO_2169 | CSIRO_1512 | CSIRO_2169 | CSIRO_1512 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.998 |
| CSIRO_2169 | CSIRO_3304 | CSIRO_2169 | CSIRO_3304 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.990 |
| CSIRO_2169 | CSIRO_3858 | CSIRO_2169 | CSIRO_3858 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.919 |
| CSIRO_2596 | CSIRO_3858 | CSIRO_2596 | CSIRO_3858 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.667 |
| CSIRO_3304 | CSIRO_1512 | CSIRO_3304 | CSIRO_1512 | Porphobilinogen synthase; Belongs to the ALAD family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.961 |
| CSIRO_3304 | CSIRO_2169 | CSIRO_3304 | CSIRO_2169 | Porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.990 |
| CSIRO_3304 | CSIRO_3858 | CSIRO_3304 | CSIRO_3858 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.973 |
| CSIRO_3855 | CSIRO_0671 | CSIRO_3855 | CSIRO_0671 | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | Aspartokinase; Belongs to the aspartokinase family. | 0.462 |
| CSIRO_3855 | CSIRO_3856 | CSIRO_3855 | CSIRO_3856 | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | UDP-N-acetylglucosamine 4,6-dehydratase. | 0.978 |
| CSIRO_3855 | CSIRO_3857 | CSIRO_3855 | CSIRO_3857 | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | N-acetylneuraminate synthase. | 0.934 |
| CSIRO_3855 | CSIRO_3858 | CSIRO_3855 | CSIRO_3858 | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.662 |
| CSIRO_3855 | CSIRO_3859 | CSIRO_3855 | CSIRO_3859 | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | Pseudaminic acid cytidylyltransferase. | 0.943 |
| CSIRO_3856 | CSIRO_3855 | CSIRO_3856 | CSIRO_3855 | UDP-N-acetylglucosamine 4,6-dehydratase. | 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(lipid carrier) aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. | 0.978 |