| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_0254 | CSIRO_3304 | CSIRO_0254 | CSIRO_3304 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.419 |
| CSIRO_0254 | CSIRO_4243 | CSIRO_0254 | CSIRO_4243 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase. | 0.785 |
| CSIRO_0254 | bioB | CSIRO_0254 | CSIRO_1345 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.868 |
| CSIRO_0254 | bioD | CSIRO_0254 | CSIRO_4242 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.946 |
| CSIRO_0254 | gcvP | CSIRO_0254 | CSIRO_3708 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.724 |
| CSIRO_3304 | CSIRO_0254 | CSIRO_3304 | CSIRO_0254 | Porphobilinogen synthase; Belongs to the ALAD family. | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.419 |
| CSIRO_3304 | CSIRO_3858 | CSIRO_3304 | CSIRO_3858 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.975 |
| CSIRO_3304 | CSIRO_4241 | CSIRO_3304 | CSIRO_4241 | Porphobilinogen synthase; Belongs to the ALAD family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.419 |
| CSIRO_3304 | CSIRO_4243 | CSIRO_3304 | CSIRO_4243 | Porphobilinogen synthase; Belongs to the ALAD family. | 8-amino-7-oxononanoate synthase. | 0.710 |
| CSIRO_3304 | acpP | CSIRO_3304 | CSIRO_2617 | Porphobilinogen synthase; Belongs to the ALAD family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.434 |
| CSIRO_3681 | CSIRO_4243 | CSIRO_3681 | CSIRO_4243 | Low-specificity L-threonine aldolase. | 8-amino-7-oxononanoate synthase. | 0.680 |
| CSIRO_3681 | gcvP | CSIRO_3681 | CSIRO_3708 | Low-specificity L-threonine aldolase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.901 |
| CSIRO_3681 | glyA | CSIRO_3681 | CSIRO_3297 | Low-specificity L-threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.874 |
| CSIRO_3858 | CSIRO_3304 | CSIRO_3858 | CSIRO_3304 | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.975 |
| CSIRO_3858 | CSIRO_4243 | CSIRO_3858 | CSIRO_4243 | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase. | 0.681 |
| CSIRO_3858 | acpP | CSIRO_3858 | CSIRO_2617 | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.773 |
| CSIRO_3858 | glyA | CSIRO_3858 | CSIRO_3297 | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.408 |
| CSIRO_4241 | CSIRO_3304 | CSIRO_4241 | CSIRO_3304 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.419 |
| CSIRO_4241 | CSIRO_4243 | CSIRO_4241 | CSIRO_4243 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase. | 0.995 |
| CSIRO_4241 | bioB | CSIRO_4241 | CSIRO_1345 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.974 |