| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV65771.1 | ADV65772.1 | Deima_0107 | Deima_0108 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | Haloacetate dehalogenase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: sro:Sros_5417 alpha/beta fold family hydrolase; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Haloacetate dehalogenase; SPTR: Alpha/beta fold family hydrolase; PFAM: alpha/beta hydrolase fold. | 0.696 |
| ADV65771.1 | ADV65834.1 | Deima_0107 | Deima_0170 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: asa:ASA_2347 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-synthase; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.908 |
| ADV65771.1 | ADV66275.1 | Deima_0107 | Deima_0618 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | 0.787 |
| ADV65771.1 | ADV66344.1 | Deima_0107 | Deima_0688 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | 0.767 |
| ADV65771.1 | ADV67103.1 | Deima_0107 | Deima_1454 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR013027; KEGG: dge:Dgeo_1576 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.913 |
| ADV65771.1 | ADV67248.1 | Deima_0107 | Deima_1599 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: nhl:Nhal_0691 cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Selenocysteine lyase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily. | 0.909 |
| ADV65771.1 | ADV67782.1 | Deima_0107 | Deima_2142 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: dge:Dgeo_0011 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.908 |
| ADV65771.1 | ADV67862.1 | Deima_0107 | Deima_2224 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...] | 0.692 |
| ADV65771.1 | ADV68539.1 | Deima_0107 | Deima_2910 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR005746; KEGG: ddr:Deide_18600 putative thioredoxin; PFAM: Thioredoxin domain; SPTR: Putative Thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. | 0.719 |
| ADV65771.1 | sigA | Deima_0107 | Deima_2326 | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.670 |
| ADV65772.1 | ADV65771.1 | Deima_0108 | Deima_0107 | Haloacetate dehalogenase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: sro:Sros_5417 alpha/beta fold family hydrolase; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Haloacetate dehalogenase; SPTR: Alpha/beta fold family hydrolase; PFAM: alpha/beta hydrolase fold. | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | 0.696 |
| ADV65834.1 | ADV65771.1 | Deima_0170 | Deima_0107 | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: asa:ASA_2347 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-synthase; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | 0.908 |
| ADV65834.1 | ADV67103.1 | Deima_0170 | Deima_1454 | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: asa:ASA_2347 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-synthase; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR013027; KEGG: dge:Dgeo_1576 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.902 |
| ADV65834.1 | ADV67782.1 | Deima_0170 | Deima_2142 | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: asa:ASA_2347 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-synthase; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: dge:Dgeo_0011 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.903 |
| ADV66275.1 | ADV65771.1 | Deima_0618 | Deima_0107 | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | 0.787 |
| ADV66275.1 | ADV66344.1 | Deima_0618 | Deima_0688 | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | 0.442 |
| ADV66275.1 | ADV67103.1 | Deima_0618 | Deima_1454 | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR013027; KEGG: dge:Dgeo_1576 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.580 |
| ADV66275.1 | ADV67862.1 | Deima_0618 | Deima_2224 | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...] | 0.556 |
| ADV66275.1 | ADV68539.1 | Deima_0618 | Deima_2910 | COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dge:Dgeo_0122 redoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Redoxin; PFAM: AhpC/TSA family. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR005746; KEGG: ddr:Deide_18600 putative thioredoxin; PFAM: Thioredoxin domain; SPTR: Putative Thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. | 0.644 |
| ADV66344.1 | ADV65771.1 | Deima_0688 | Deima_0107 | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | Cyclic nucleotide-binding protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR000595: IPR013027; KEGG: bph:Bphy_4599 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain; PRIAM: Thioredoxin-disulfide reductase; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain. | 0.767 |