STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65864.1High-affinity nickel-transporter; InterPro IPR011541; KEGG: ddr:Deide_2p01650 hypothetical protein; PFAM: Nickel/cobalt transporter, high-affinity; SPTR: Putative uncharacterized protein; PFAM: High-affinity nickel-transport protein. (226 aa)    
Predicted Functional Partners:
ADV65871.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363: IPR003723: IPR000878; KEGG: hse:Hsero_2649 bifunctional precorrin-3 methyltransferase/precorrin-6x reductase oxidoreductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase., Precorrin-6A reductase; SPTR: Bifunctional: precorrin-3 methyltransferase and precorrin-6x reductase oxidoreductase protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; Cobalamin (vitamin B12) biosynthesis [...]
       0.884
ADV65865.1
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR012818: IPR000878; KEGG: ddr:Deide_2p01570 cobalt-precorrin-6Y C(5)-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Putative precorrin-6B methylase 1; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
 
     0.865
ADV65866.1
Sirohydrochlorin ferrochelatase., Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR002762: IPR003722; KEGG: rsl:RPSI07_mp0507 putative precorrin-8X methylmutase (CobH/CbiC); PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; Cobalamin (vitamin B12) biosynthesis CbiX; PRIAM: Sirohydrochlorin ferrochelatase., Precorrin-8X methylmutase; SPTR: Putative precorrin-8X methylmutase (CobH/CbiC); PFAM: Precorrin-8X methylmutase; CbiX.
  
    0.850
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.847
ADV65872.1
Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR011629: IPR003495; KEGG: rsl:RPSI07_mp0501 putative cobalamin biosynthesis protein (CobW); PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal; SMART: Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal; SPTR: Putative cobalamin biosynthesis protein (CobW); PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain.
     
 0.825
ADV65868.1
COGs: COG2243 Precorrin-2 methylase; InterPro IPR006364: IPR000878; KEGG: rso:RSp0621 precorrin-2 C20-methyltransferase protein; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-2 c20-methyltransferase protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase.
       0.821
ADV65869.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362: IPR000878; KEGG: hse:Hsero_2651 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase.
       0.821
ADV65870.1
COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: ddr:Deide_2p01620 cobalamin biosynthesis protein CbiG; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal.
       0.821
ADV65863.1
Hypothetical protein; KEGG: cag:Cagg_2652 MCP methyltransferase, CheR-type with Tpr repeats; SPTR: MCP methyltransferase, CheR-type with Tpr repeats.
       0.773
ADV65874.1
COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593: IPR002035: IPR011704; KEGG: hse:Hsero_2656 Mg-chelatase subunit ChlI protein; PFAM: ATPase, AAA-5; von Willebrand factor, type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor, type A; ATPase, AAA+ type, core; SPTR: Mg-chelatase subunit ChlI protein; PFAM: von Willebrand factor type A domain; AAA domain (dynein-related subfamily).
       0.755
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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