Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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ADV66500.1Bifunctional DNA primase/polymerase; COGs: COG0358 DNA primase; InterPro IPR015330; KEGG: dra:DR_0530 hypothetical protein; SMART: DNA primase/polymerase, bifunctional, N-terminal; SPTR: Putative uncharacterized protein; PFAM: Bifunctional DNA primase/polymerase, N-terminal. (630 aa)    
Predicted Functional Partners:
ADV66501.1
DnaB domain protein helicase domain protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: rpf:Rpic12D_2278 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; SPTR: DnaB domain protein helicase domain protein; PFAM: DnaB-like helicase C terminal domain.
  
 
 0.907
ADV68636.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 0.738
ADV66283.1
Dynamin family protein; InterPro IPR001401; KEGG: dge:Dgeo_2106 dynamin; PFAM: Dynamin, GTPase domain; SPTR: Dynamin-like GTPase; PFAM: Dynamin family; TIGRFAM: small GTP-binding protein domain.
   
  
 0.650
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
  
 0.650
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.605
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.583
ADV65716.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
  
 0.563
ADV66502.1
KEGG: smd:Smed_1664 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.524
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 
 0.518
ADV67604.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583: IPR002932: IPR002489; KEGG: mrb:Mrub_1802 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
 
   
 0.506
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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