STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (445 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.994
ADV66843.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterProIPR020822: IPR006218: IPR002701: IPR010954: IPR 006268; KEGG: ddr:Deide_05640 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SMART: Chorismate mutase; SPTR: Putative 3-deoxy-7-phosphoheptulonate synthase (Phospho-2-dehydro-3-deoxyheptonate aldolase); TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; Chorismate mutase, Gram-positive bacteria/Deinococcus; PFAM: Choris [...]
 
  
 0.993
ADV67186.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.989
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.987
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.985
ADV67608.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099: IPR002912; KEGG: ddr:Deide_10960 putative prephenate dehydrogenase (chorismate mutase--prephenate dehydrogenase); PFAM: Prephenate dehydrogenase; Amino acid-binding ACT; PRIAM: Prephenate dehydrogenase; SPTR: Putative prephenate dehydrogenase (Chorismate mutase--prephenate dehydrogenase); PFAM: Prephenate dehydrogenase.
 
  
 0.932
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: dge:Dgeo_2220 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
 
  
 0.906
ADV66936.1
Glutamine amidotransferase of anthranilate synthase; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006221: IPR006805: IPR015890: IPR000991; KEGG: dge:Dgeo_0498 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; TIGRFAM: Anthranilate synthase, glutamine amidotransferase do [...]
 
   
 0.708
ADV66558.1
NHL repeat containing protein; COGs: COG2133 Glucose/sorbosone dehydrogenase; InterPro IPR001258; KEGG: ddr:Deide_08970 putative L-sorbosone dehydrogenase; PFAM: NHL repeat; SPTR: Putative L-sorbosone dehydrogenase; PFAM: Glucose / Sorbosone dehydrogenase; Membrane bound L-sorbosone dehydrogenase.
       0.699
ADV67470.1
COGs: COG0527 Aspartokinase; InterPro IPR001048: IPR002912: IPR005260: IPR001341; KEGG: dge:Dgeo_1127 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
  
 0.615
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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