Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV66566.1COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR022643: IPR005730; KEGG: dge:Dgeo_1317 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, C-terminal; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase. (393 aa)    
Predicted Functional Partners:
ADV66562.1
COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: dge:Dgeo_0999 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase / Homospermidine synthase; SPTR: Saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase.
 
 
 0.981
ADV66564.1
Drug resistance transporter, EmrB/QacA subfamily; InterPro IPR004638: IPR011701; KEGG: rxy:Rxyl_0617 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
       0.549
ADV66565.1
Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cts:Ctha_2502 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; PFAM: MarR family.
       0.549
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.514
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
 
  
 0.490
hisI
Phosphoribosyl-ATP pyrophosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR008179: IPR002496: IPR021130: IPR023019; KEGG: dra:DR_0733 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Histidine biosynthesis bifunctional protein hisIE; TIGRFAM: Phosphoribosyl-A [...]
  
  
 0.466
ADV68708.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dra:DR_0623 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
  
 0.459
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.444
ADV68369.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.433
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
 
 0.425
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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