Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV66590.1Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). (263 aa)    
Predicted Functional Partners:
ADV66591.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.826
ADV66592.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.826
ADV66593.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...]
       0.826
ADV66219.1
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: dge:Dgeo_0336 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix.
 
  
 0.703
ADV66589.1
COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein.
       0.662
ADV66594.1
PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain.
       0.610
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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