| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV66216.1 | ADV66591.1 | Deima_0557 | Deima_0938 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
| ADV66216.1 | ADV66592.1 | Deima_0557 | Deima_0939 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.473 |
| ADV66216.1 | ADV66593.1 | Deima_0557 | Deima_0940 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.562 |
| ADV66216.1 | ADV66936.1 | Deima_0557 | Deima_1285 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | Glutamine amidotransferase of anthranilate synthase; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006221: IPR006805: IPR015890: IPR000991; KEGG: dge:Dgeo_0498 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; TIGRFAM: Anthranilate synthase, glutamine amidotransferase do [...] | 0.426 |
| ADV66216.1 | ADV68801.1 | Deima_0557 | Deima_3173 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645: IPR013221: IPR004101; KEGG: dge:Dgeo_0083 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: Folylpolyglutamate synthetase; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | 0.921 |
| ADV66589.1 | ADV66590.1 | Deima_0936 | Deima_0937 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 0.662 |
| ADV66589.1 | ADV66591.1 | Deima_0936 | Deima_0938 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.662 |
| ADV66589.1 | ADV66592.1 | Deima_0936 | Deima_0939 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.662 |
| ADV66589.1 | ADV66593.1 | Deima_0936 | Deima_0940 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.662 |
| ADV66589.1 | ADV66594.1 | Deima_0936 | Deima_0941 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.524 |
| ADV66590.1 | ADV66589.1 | Deima_0937 | Deima_0936 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 0.662 |
| ADV66590.1 | ADV66591.1 | Deima_0937 | Deima_0938 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.826 |
| ADV66590.1 | ADV66592.1 | Deima_0937 | Deima_0939 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.826 |
| ADV66590.1 | ADV66593.1 | Deima_0937 | Deima_0940 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.826 |
| ADV66590.1 | ADV66594.1 | Deima_0937 | Deima_0941 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.610 |
| ADV66591.1 | ADV66216.1 | Deima_0938 | Deima_0557 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR001645; KEGG: dge:Dgeo_0333 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | 0.996 |
| ADV66591.1 | ADV66589.1 | Deima_0938 | Deima_0936 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 0.662 |
| ADV66591.1 | ADV66590.1 | Deima_0938 | Deima_0937 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 0.826 |
| ADV66591.1 | ADV66592.1 | Deima_0938 | Deima_0939 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| ADV66591.1 | ADV66593.1 | Deima_0938 | Deima_0940 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.999 |