| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV65832.1 | ADV66594.1 | Deima_0168 | Deima_0941 | Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR003018; KEGG: ddr:Deide_1p00440 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.718 |
| ADV65832.1 | ADV66955.1 | Deima_0168 | Deima_1304 | Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR003018; KEGG: ddr:Deide_1p00440 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442: IPR001258: IPR002290: IPR020635; KEGG: ddr:Deide_13750 putative serine/threonine protein kinase; putative membrane protein; PFAM: Serine/threonine-protein kinase-like domain; NHL repeat; PRIAM: Calcium/calmodulin-dependent protein kinase; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Putative Serine/threonine protein kinase; putative membrane protein; PFAM: Protein kinase domain. | 0.620 |
| ADV65832.1 | ADV68914.1 | Deima_0168 | Deima_3287 | Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR003018; KEGG: ddr:Deide_1p00440 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045; KEGG: dge:Dgeo_0229 protein serine/threonine phosphatases; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C. | 0.428 |
| ADV66589.1 | ADV66590.1 | Deima_0936 | Deima_0937 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 0.662 |
| ADV66589.1 | ADV66591.1 | Deima_0936 | Deima_0938 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.662 |
| ADV66589.1 | ADV66592.1 | Deima_0936 | Deima_0939 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.662 |
| ADV66589.1 | ADV66593.1 | Deima_0936 | Deima_0940 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.662 |
| ADV66589.1 | ADV66594.1 | Deima_0936 | Deima_0941 | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.524 |
| ADV66590.1 | ADV66589.1 | Deima_0937 | Deima_0936 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 0.662 |
| ADV66590.1 | ADV66591.1 | Deima_0937 | Deima_0938 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.826 |
| ADV66590.1 | ADV66592.1 | Deima_0937 | Deima_0939 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.826 |
| ADV66590.1 | ADV66593.1 | Deima_0937 | Deima_0940 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.826 |
| ADV66590.1 | ADV66594.1 | Deima_0937 | Deima_0941 | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.610 |
| ADV66591.1 | ADV66589.1 | Deima_0938 | Deima_0936 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 0.662 |
| ADV66591.1 | ADV66590.1 | Deima_0938 | Deima_0937 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955). | 0.826 |
| ADV66591.1 | ADV66592.1 | Deima_0938 | Deima_0939 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| ADV66591.1 | ADV66593.1 | Deima_0938 | Deima_0940 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...] | 0.999 |
| ADV66591.1 | ADV66594.1 | Deima_0938 | Deima_0941 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. | 0.675 |
| ADV66591.1 | ADV66595.1 | Deima_0938 | Deima_0942 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ddr:Deide_06740 putative cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Putative cysteine desulfurase; PFAM: Aminotransferase class-V. | 0.482 |
| ADV66592.1 | ADV66589.1 | Deima_0939 | Deima_0936 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein. | 0.662 |