Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV66594.1PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: ddr:Deide_06750 putative PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative PASTA domain protein; PFAM: PASTA domain. (536 aa)    
Predicted Functional Partners:
ADV65832.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR003018; KEGG: ddr:Deide_1p00440 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
   
 
 0.718
ADV66592.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
     0.694
ADV66591.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
     0.675
ADV68914.1
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045; KEGG: dge:Dgeo_0229 protein serine/threonine phosphatases; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C.
 
 
 0.660
ADV66593.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dge:Dgeo_0398 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); T [...]
 
     0.658
ADV66595.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ddr:Deide_06740 putative cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Putative cysteine desulfurase; PFAM: Aminotransferase class-V.
       0.630
ADV66590.1
Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: dge:Dgeo_0395 hypothetical protein; PFAM: Protein of unknown function DUF955; SPTR: Zn dependent hydrolase fused to HTH domain, IrrE ortholog; PFAM: Domain of unknown function (DUF955).
       0.610
ADV66589.1
COGs: COG4281 Acyl-CoA-binding protein; InterPro IPR000582; KEGG: dge:Dgeo_0394 acyl-CoA-binding protein; PFAM: Acyl-CoA-binding protein, ACBP; SPTR: Acyl-coA-binding protein, ACBP; PFAM: Acyl CoA binding protein.
 
     0.524
ADV66955.1
COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442: IPR001258: IPR002290: IPR020635; KEGG: ddr:Deide_13750 putative serine/threonine protein kinase; putative membrane protein; PFAM: Serine/threonine-protein kinase-like domain; NHL repeat; PRIAM: Calcium/calmodulin-dependent protein kinase; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Putative Serine/threonine protein kinase; putative membrane protein; PFAM: Protein kinase domain.
 
 
 0.519
ADV68618.1
KEGG: dge:Dgeo_1817 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.511
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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