STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV66612.1UPF0301 protein yqgE; COGs: COG1678 Putative transcriptional regulator protein; HAMAP: Protein of unknown function DUF179; InterPro IPR003774; KEGG: ddr:Deide_05660 hypothetical protein; PFAM: Protein of unknown function DUF179; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family. (173 aa)    
Predicted Functional Partners:
ADV65716.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 0.983
ADV66537.1
Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; InterPro IPR004821; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein; SPTR: ATPase/kinase involved in NAD metabolism-like protein; TIGRFAM: Cytidyltransferase-related; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain.
   
    0.834
lon-2
Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.722
ADV68827.1
Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
  
 0.698
ADV65666.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.625
ADV68623.1
KEGG: dra:DR_0948 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.573
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.519
ADV66952.1
COGs: COG2142 Succinate dehydrogenase hydrophobic anchor subunit; InterPro IPR000701; KEGG: dge:Dgeo_0888 succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit; SPTR: Succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
   
    0.489
tdk
COGs: COG1435 Thymidine kinase; HAMAP: Thymidine kinase, subgroup; InterPro IPR020634: IPR001267; KEGG: dge:Dgeo_0578 thymidine kinase; PFAM: Thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase.
   
  
 0.486
ADV66690.1
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: dge:Dgeo_2423 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Stomatin/prohibitin family protein; PFAM: SPFH domain / Band 7 family.
   
    0.463
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.