STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV66888.1(Uracil-5)-methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: ddr:Deide_04430 putative (uracil-5)-methyltransferase; PFAM: (Uracil-5)-methyltransferase; SPTR: Putative (Uracil-5)-methyltransferase; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (407 aa)    
Predicted Functional Partners:
ADV66889.1
KEGG: dge:Dgeo_1778 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.729
ADV67602.1
NusB/RsmB/TIM44; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: dge:Dgeo_1498 NusB/RsmB/TIM44; PFAM: NusB/RsmB/TIM44; Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: rRNA methyltransferase, sun family protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.593
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
  
    0.557
rsmI
Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.543
hisI
Phosphoribosyl-ATP pyrophosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR008179: IPR002496: IPR021130: IPR023019; KEGG: dra:DR_0733 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Histidine biosynthesis bifunctional protein hisIE; TIGRFAM: Phosphoribosyl-A [...]
  
    0.523
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.508
ADV67431.1
tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: ddr:Deide_10321 putative rRNA (adenosine-2-O-)-methyltransferase (SpoU rRNA methylase); PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: Putative rRNA (Adenosine-2-O-)-methyltransferase (SpoU rRNA methylase); PFAM: SpoU rRNA Methylase family.
 
  
 0.488
ADV66789.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: dge:Dgeo_2022 RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase TrmH, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding met [...]
 
  
 0.485
ADV68009.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.481
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.476
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.