STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS2MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (761 aa)    
Predicted Functional Partners:
ADV68142.1
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA.
 
 
0.943
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.798
ADV67323.1
COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616: IPR008532; KEGG: dge:Dgeo_1423 fibronectin-binding A-like protein; PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; SPTR: Fibronectin-binding A-like protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).
 
     0.747
dacA
Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
     0.644
ADV67314.1
Hypothetical protein; KEGG: ddr:Deide_05001 conserved hypothetical protein, precursor; SPTR: Putative uncharacterized protein.
       0.630
ADV66845.1
PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013: IPR002054: IPR003583: IPR003141; KEGG: ddr:Deide_07030 putative DNA polymerase, family X; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; DNA-directed DNA polymerase X; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Putative DNA polymerase, family X; PFAM: PHP domain.
  
  
 0.627
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.619
ADV67313.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633; KEGG: azo:azo1278 EAL/GGDEF/PAS/PAC-domain-containing signalling protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: EAL/GGDEF/PAS/PAC-domain containing signalling protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
       0.576
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.567
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
   0.551
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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