Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADV67344.1Peptidase M16C associated domain protein; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765: IPR007863: IPR013578; KEGG: dge:Dgeo_1643 peptidase M16C associated; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase M16C associated; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16). (968 aa)    
Predicted Functional Partners:
ADV67345.1
Ig family protein; InterPro IPR008009; KEGG: ddr:Deide_05420 hypothetical protein; PFAM: Putative Ig; SPTR: Putative uncharacterized protein.
       0.673
ADV67346.1
KEGG: dge:Dgeo_1645 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.673
ADV67347.1
KEGG: dge:Dgeo_1646 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.673
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.589
ADV67343.1
KEGG: mta:Moth_0338 hypothetical protein; SPTR: Autotransporter-associated beta strand repeat protein.
       0.548
ADV66159.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476; KEGG: dge:Dgeo_2339 transketolase, central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoisovalerate dehydrogenase, ODBB; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimid [...]
    
   0.499
ADV66750.1
COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476; KEGG: dge:Dgeo_1562 transketolase, central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoisovalerate dehydrogenase, OdbB; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
   0.499
ADV65725.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: ddr:Deide_01410 putative Xaa-Pro aminopeptidase; PFAM: Peptidase M24, structural domain; SPTR: Putative Xaa-pro aminopeptidase; PFAM: Metallopeptidase family M24.
   
 
 0.476
ADV67465.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994; KEGG: dra:DR_1246 proline dipeptidase; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Proline dipeptidase; manually curated; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain.
   
 
 0.476
ADV67092.1
InterPro IPR003660; KEGG: dge:Dgeo_1467 sensor protein; PFAM: HAMP linker domain; SMART: HAMP linker domain; SPTR: Putative sensor with HAMP domain; PFAM: HAMP domain.
  
     0.431
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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