STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV67608.1COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099: IPR002912; KEGG: ddr:Deide_10960 putative prephenate dehydrogenase (chorismate mutase--prephenate dehydrogenase); PFAM: Prephenate dehydrogenase; Amino acid-binding ACT; PRIAM: Prephenate dehydrogenase; SPTR: Putative prephenate dehydrogenase (Chorismate mutase--prephenate dehydrogenase); PFAM: Prephenate dehydrogenase. (361 aa)    
Predicted Functional Partners:
ADV66843.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterProIPR020822: IPR006218: IPR002701: IPR010954: IPR 006268; KEGG: ddr:Deide_05640 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SMART: Chorismate mutase; SPTR: Putative 3-deoxy-7-phosphoheptulonate synthase (Phospho-2-dehydro-3-deoxyheptonate aldolase); TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; Chorismate mutase, Gram-positive bacteria/Deinococcus; PFAM: Choris [...]
 0.986
ADV67655.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086; KEGG: ddr:Deide_11150 putative prephenate dehydratase; PFAM: Prephenate dehydratase; PRIAM: Prephenate dehydratase; SPTR: Putative prephenate dehydratase; PFAM: Prephenate dehydratase.
 
 0.968
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR004839: IPR005861; KEGG: dge:Dgeo_0118 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.966
ADV67737.1
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: dra:DR_B0011 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/classII; SPTR: Histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II.
  
 
 0.966
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.932
ADV68708.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dra:DR_0623 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
 
 0.925
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.877
ADV67186.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.755
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.692
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: dge:Dgeo_2220 cytidylate kinase; PFAM: Cytidylate kinase domain; PRIAM: Cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
 
  
 0.678
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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