| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV65780.1 | ADV65958.1 | Deima_0116 | Deima_0297 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | 0.905 |
| ADV65780.1 | ADV66076.1 | Deima_0116 | Deima_0416 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: rmr:Rmar_1466 lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.939 |
| ADV65780.1 | ADV66661.1 | Deima_0116 | Deima_1008 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ddr:Deide_21140 putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| ADV65780.1 | ADV67640.1 | Deima_0116 | Deima_1995 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: dra:DR_0929 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase; PFAM: Acylphosphatase. | 0.900 |
| ADV65780.1 | ADV67682.1 | Deima_0116 | Deima_2039 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_2396 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. | 0.905 |
| ADV65780.1 | ADV67761.1 | Deima_0116 | Deima_2119 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.439 |
| ADV65780.1 | ackA | Deima_0116 | Deima_1846 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.910 |
| ADV65780.1 | acsA | Deima_0116 | Deima_0191 | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.905 |
| ADV65958.1 | ADV65780.1 | Deima_0297 | Deima_0116 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | 0.905 |
| ADV65958.1 | ADV66076.1 | Deima_0297 | Deima_0416 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: rmr:Rmar_1466 lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.911 |
| ADV65958.1 | ADV66661.1 | Deima_0297 | Deima_1008 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ddr:Deide_21140 putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.931 |
| ADV65958.1 | ADV67640.1 | Deima_0297 | Deima_1995 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: dra:DR_0929 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase; PFAM: Acylphosphatase. | 0.900 |
| ADV65958.1 | ADV67682.1 | Deima_0297 | Deima_2039 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_2396 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. | 0.923 |
| ADV65958.1 | ADV67761.1 | Deima_0297 | Deima_2119 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
| ADV65958.1 | ackA | Deima_0297 | Deima_1846 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.923 |
| ADV65958.1 | acsA | Deima_0297 | Deima_0191 | Acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dge:Dgeo_1750 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.908 |
| ADV65970.1 | ADV66661.1 | Deima_0309 | Deima_1008 | Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: mpo:Mpop_1309 amidase; PFAM: Amidase; SPTR: Amidase; PFAM: Amidase. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ddr:Deide_21140 putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Putative NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.905 |
| ADV65970.1 | ADV67640.1 | Deima_0309 | Deima_1995 | Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: mpo:Mpop_1309 amidase; PFAM: Amidase; SPTR: Amidase; PFAM: Amidase. | COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: dra:DR_0929 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase; PFAM: Acylphosphatase. | 0.903 |
| ADV65970.1 | ADV67656.1 | Deima_0309 | Deima_2011 | Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: mpo:Mpop_1309 amidase; PFAM: Amidase; SPTR: Amidase; PFAM: Amidase. | Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: dge:Dgeo_1333 amidase; PFAM: Amidase; PRIAM: Amidase; SPTR: Amidase; PFAM: Amidase. | 0.927 |
| ADV66076.1 | ADV65780.1 | Deima_0416 | Deima_0116 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: rmr:Rmar_1466 lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...] | 0.939 |