STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV67657.1Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR013656: IPR006674: IPR000014: IPR001610: IPR 003607; KEGG: tra:Trad_1982 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; PAS fold-4; SMART: PAS; PAC motif; Metal-dependent phosphohydrolase, HD domain; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: PAS; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box. (337 aa)    
Predicted Functional Partners:
ADV67200.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633; KEGG: ddr:Deide_18060 putative diguanylate cyclase/phosphodiesterase; putative membrane protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate cyclase/phosphodiesterase; putative membrane protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: d [...]
 
 0.878
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
 
 
 0.851
ADV65939.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: ddr:Deide_2p00540 putative response regulator, CheY, putative response regulator PleD; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Putative response regulator, CheY, putative response regulator pleD; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 0.791
ADV65785.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018: IPR007891: IPR003660; KEGG: ddr:Deide_18070 putative diguanylate-cyclase; PFAM: Diguanylate cyclase, predicted; CHASE3; HAMP linker domain; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: HAMP domain; GGDEF domain; CHASE3 domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 0.748
ADV67986.1
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: pin:Ping_0273 diguanylate cyclase with PAS/PAC sensor; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.745
ADV66014.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR003018: IPR000160; KEGG: afw:Anae109_2240 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; GAF; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Domain of unknown function (DUF3369); GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase [...]
 
 0.735
ADV66054.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR019734; KEGG: ddr:Deide_21850 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.731
ADV65980.1
Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR003018: IPR001867; KEGG: dge:Dgeo_2479 diguanylate cyclase with GAF sensor; PFAM: GAF; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, C-terminal; GAF; SPTR: Diguanylate cyclase with GAF sensor; PFAM: GAF domain; Transcriptional regulatory protein, C terminal.
 
 
 0.715
ADV66058.1
GAF domain protein; InterPro IPR003018; KEGG: ddr:Deide_1p01751 putative diguanylate cyclase (GGDEF domain) with GAF sensor; PFAM: GAF; SMART: GAF; SPTR: Putative Diguanylate cyclase (GGDEF domain) with GAF sensor; PFAM: GAF domain.
 
 
 0.715
ADV68216.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR003018: IPR000160; KEGG: sti:Sthe_0405 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.704
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
Server load: low (20%) [HD]