| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV67662.1 | pyrD | Deima_2018 | Deima_2019 | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dra:DR_2094 rrf2 protein; PFAM: Transcription regulator Rrf2; SPTR: Rrf2 protein; TIGRFAM: Transcription regulator Rrf2; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator). | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.721 |
| carA | carB | Deima_0951 | Deima_0945 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | 0.999 |
| carA | guaA | Deima_0951 | Deima_1639 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.641 |
| carA | pyrB | Deima_0951 | Deima_2022 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR006132: IPR006131: IPR002082; KEGG: dra:DR_1109 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoy [...] | 0.999 |
| carA | pyrC | Deima_0951 | Deima_2021 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
| carA | pyrD | Deima_0951 | Deima_2019 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.944 |
| carA | pyrE | Deima_0951 | Deima_2792 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.931 |
| carA | pyrF | Deima_0951 | Deima_0815 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; InterPro IPR011995: IPR001754; KEGG: ddr:Deide_17030 putative orotidine-5 -phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP de [...] | 0.942 |
| carA | pyrR | Deima_0951 | Deima_2023 | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.712 |
| carB | carA | Deima_0945 | Deima_0951 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | 0.999 |
| carB | guaA | Deima_0945 | Deima_1639 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.860 |
| carB | pheT | Deima_0945 | Deima_3291 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR005146: IPR005147: IPR005121: IPR004532: IPR 002547; KEGG: dge:Dgeo_0224 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subuni [...] | 0.477 |
| carB | pyrB | Deima_0945 | Deima_2022 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR006132: IPR006131: IPR002082; KEGG: dra:DR_1109 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoy [...] | 0.999 |
| carB | pyrC | Deima_0945 | Deima_2021 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
| carB | pyrD | Deima_0945 | Deima_2019 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.961 |
| carB | pyrE | Deima_0945 | Deima_2792 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.942 |
| carB | pyrF | Deima_0945 | Deima_0815 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; InterPro IPR011995: IPR001754; KEGG: ddr:Deide_17030 putative orotidine-5 -phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP de [...] | 0.969 |
| carB | pyrR | Deima_0945 | Deima_2023 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.897 |
| guaA | carA | Deima_1639 | Deima_0951 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474: IPR000991: IPR006274; KEGG: dge:Dgeo_2060 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Be [...] | 0.641 |
| guaA | carB | Deima_1639 | Deima_0945 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR006275; KEGG: ddr:Deide_00700 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domai [...] | 0.860 |