Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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ADV67788.1Iron-sulfur cluster loop; COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265: IPR003651; KEGG: dge:Dgeo_0785 HhH-GPD; PFAM: Endonuclease III-like, iron-sulphur cluster loop motif; HhH-GPD domain; SMART: HhH-GPD domain; SPTR: Endonuclease III, alpha helical glycosidase superfamily; PFAM: HhH-GPD superfamily base excision DNA repair protein. (247 aa)    
Predicted Functional Partners:
ADV66193.1
HhH-GPD family protein; COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265: IPR003651; KEGG: dge:Dgeo_2290 HhH-GPD; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SMART: HhH-GPD domain; SPTR: HhH-GPD; PFAM: HhH-GPD superfamily base excision DNA repair protein.
  
  
 
0.923
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 
0.923
ADV67754.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR005135: IPR000097: IPR004808; KEGG: ddr:Deide_03250 putative exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Putative exodeoxyribonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
  
 0.646
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.622
ADV67787.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: amt:Amet_2940 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.
       0.561
ADV65816.1
Parallel beta-helix repeat; InterPro IPR022441: IPR006626; KEGG: ddr:Deide_1p01370 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Parallel beta-helix repeat-2; TIGRFAM: parallel beta-helix repeat (two copies).
  
   
 0.406
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 
 0.404
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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