Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV67793.1Aminoglycoside phosphotransferase; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: lpp:plpp0135 hypothetical protein; PFAM: Aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: Phosphotransferase enzyme family. (314 aa)    
Predicted Functional Partners:
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
       0.572
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
       0.572
ADV67794.1
PAS fold-4 domain protein; InterPro IPR013656; KEGG: rlt:Rleg2_1658 PAS/PAC sensor hybrid histidine kinase; PFAM: PAS fold-4; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: PAS fold.
       0.553
ADV66265.1
Aminoglycoside phosphotransferase; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: ppg:PputGB1_1793 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family.
  
     0.473
ADV68013.1
Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: ddr:Deide_07480 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; PFAM: Major Facilitator Superfamily.
  
     0.418
ADV66379.1
GCN5-related N-acetyltransferase; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: ddr:Deide_02910 putative ribosomal protein N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative Ribosomal protein N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
 
     0.410
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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