Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV67794.1PAS fold-4 domain protein; InterPro IPR013656; KEGG: rlt:Rleg2_1658 PAS/PAC sensor hybrid histidine kinase; PFAM: PAS fold-4; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: PAS fold. (243 aa)    
Predicted Functional Partners:
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
 
 
 0.862
ADV67741.1
KEGG: dge:Dgeo_0840 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.628
ADV66049.1
KEGG: vap:Vapar_1652 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.595
ADV66089.1
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR003661: IPR003594: IPR001789: IPR003018; KEGG: dge:Dgeo_2096 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; GAF; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: [...]
 
 
 0.585
ADV67251.1
Cyclase/dehydrase; COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: ddr:Deide_17270 putative cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; SPTR: Putative cyclase/dehydrase; PFAM: Polyketide cyclase / dehydrase and lipid transport.
  
     0.561
ADV67793.1
Aminoglycoside phosphotransferase; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: lpp:plpp0135 hypothetical protein; PFAM: Aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: Phosphotransferase enzyme family.
       0.553
ADV66374.1
Cyclase/dehydrase; COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: dge:Dgeo_0114 cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; SPTR: Cyclase/dehydrase; PFAM: Polyketide cyclase / dehydrase and lipid transport.
  
     0.545
kdpC
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.541
ADV66924.1
Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: dge:Dgeo_0891 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding, Gsp26; PFAM: Pyridoxamine 5'-phosphate oxidase.
  
     0.515
ADV65754.1
Protein of unknown function DUF892; COGs: COG3685 conserved hypothetical protein; InterPro IPR010287; KEGG: ddr:Deide_13500 hypothetical protein; PFAM: Protein of unknown function DUF892; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF892).
  
     0.502
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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