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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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pdxHPyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
  
 
 0.927
ADV68818.1
COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR004625: IPR013749; KEGG: dge:Dgeo_0144 pyridoxamine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Pyridoxal kinase; SPTR: Pyridoxamine kinase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase.
    
 0.921
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.920
ADV65746.1
NADP-dependent oxidoreductase domain protein; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: ara:Arad_0567 oxidoreductase protein; PFAM: NADP-dependent oxidoreductase domain; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family.
     
  0.900
ADV66418.1
NADP-dependent oxidoreductase domain protein; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: ddr:Deide_07880 putative oxidoreductase; PFAM: NADP-dependent oxidoreductase domain; SPTR: Putative oxidoreductase; PFAM: Aldo/keto reductase family.
     
  0.900
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.755
ADV67971.1
KEGG: dge:Dgeo_0444 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.698
ADV67970.1
Band 7 protein; COGs: COG2268 conserved hypothetical protein; InterPro IPR001107; KEGG: dge:Dgeo_0445 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Flotillin family protein; PFAM: SPFH domain / Band 7 family.
       0.646
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR006132: IPR006131: IPR002082; KEGG: dra:DR_1109 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoy [...]
      0.558
ADV67975.1
Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
       0.557
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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