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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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[Homology]
Score
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)    
Predicted Functional Partners:
ADV65716.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.956
tdk
COGs: COG1435 Thymidine kinase; HAMAP: Thymidine kinase, subgroup; InterPro IPR020634: IPR001267; KEGG: dge:Dgeo_0578 thymidine kinase; PFAM: Thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase.
  
 
 0.934
ADV68185.1
COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843: IPR008334; KEGG: ddr:Deide_13330 putative 5 -nucleotidases (UshA), precursor; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative 5-nucleotidases (UshA),; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
  
 
 0.925
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.923
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.920
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.919
ADV66812.1
COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843: IPR008334; KEGG: dge:Dgeo_2751 5'-nucleotidase-like; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: 5'-Nucleotidase-like protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
   
 
 0.915
ADV68009.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
 
  0.905
ADV68024.1
NGG1p interacting factor 3 protein, NIF3; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: dge:Dgeo_1982 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: NIF3 family protein, DUF34; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.
  
    0.832
ADV68025.1
InterPro IPR004360; KEGG: dge:Dgeo_1981 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/Dioxygenase family protein.
       0.766
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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