STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV68063.1COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (328 aa)    
Predicted Functional Partners:
ADV68838.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.663
ADV68061.1
Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein.
       0.634
ADV68062.1
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.634
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.561
ADV66869.1
COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: dge:Dgeo_2402 MaoC-like dehydratase; PFAM: MaoC-like dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: MaoC-like protein dehydratase; PFAM: MaoC like domain.
 
 0.511
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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