| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV65844.1 | ADV68063.1 | Deima_0180 | Deima_2425 | Hypothetical protein; COGs: COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; KEGG: fre:Franean1_4187 4'-phosphopantetheinyl transferase; SPTR: 4'-phosphopantetheinyl transferase. | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 0.410 |
| ADV66344.1 | ADV66869.1 | Deima_0688 | Deima_1218 | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: dge:Dgeo_2402 MaoC-like dehydratase; PFAM: MaoC-like dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: MaoC-like protein dehydratase; PFAM: MaoC like domain. | 0.450 |
| ADV66344.1 | ADV68063.1 | Deima_0688 | Deima_2425 | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 0.448 |
| ADV66344.1 | ADV68914.1 | Deima_0688 | Deima_3287 | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045; KEGG: dge:Dgeo_0229 protein serine/threonine phosphatases; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C. | 0.803 |
| ADV66869.1 | ADV66344.1 | Deima_1218 | Deima_0688 | COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: dge:Dgeo_2402 MaoC-like dehydratase; PFAM: MaoC-like dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: MaoC-like protein dehydratase; PFAM: MaoC like domain. | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | 0.450 |
| ADV66869.1 | ADV68063.1 | Deima_1218 | Deima_2425 | COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: dge:Dgeo_2402 MaoC-like dehydratase; PFAM: MaoC-like dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: MaoC-like protein dehydratase; PFAM: MaoC like domain. | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 0.524 |
| ADV68061.1 | ADV68062.1 | Deima_2423 | Deima_2424 | Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein. | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. | 0.773 |
| ADV68061.1 | ADV68063.1 | Deima_2423 | Deima_2425 | Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein. | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 0.634 |
| ADV68061.1 | glyA | Deima_2423 | Deima_2426 | Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.444 |
| ADV68062.1 | ADV68061.1 | Deima_2424 | Deima_2423 | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. | Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein. | 0.773 |
| ADV68062.1 | ADV68063.1 | Deima_2424 | Deima_2425 | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 0.634 |
| ADV68062.1 | glyA | Deima_2424 | Deima_2426 | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.446 |
| ADV68063.1 | ADV65844.1 | Deima_2425 | Deima_0180 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | Hypothetical protein; COGs: COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; KEGG: fre:Franean1_4187 4'-phosphopantetheinyl transferase; SPTR: 4'-phosphopantetheinyl transferase. | 0.410 |
| ADV68063.1 | ADV66344.1 | Deima_2425 | Deima_0688 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. | 0.448 |
| ADV68063.1 | ADV66869.1 | Deima_2425 | Deima_1218 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: dge:Dgeo_2402 MaoC-like dehydratase; PFAM: MaoC-like dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: MaoC-like protein dehydratase; PFAM: MaoC like domain. | 0.524 |
| ADV68063.1 | ADV68061.1 | Deima_2425 | Deima_2423 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | Protein of unknown function UPF0153; InterPro IPR005358; KEGG: ddr:Deide_02401 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein. | 0.634 |
| ADV68063.1 | ADV68062.1 | Deima_2425 | Deima_2424 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ddr:Deide_06930 putative acyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family. | 0.634 |
| ADV68063.1 | ADV68838.1 | Deima_2425 | Deima_3211 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.658 |
| ADV68063.1 | ADV68914.1 | Deima_2425 | Deima_3287 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045; KEGG: dge:Dgeo_0229 protein serine/threonine phosphatases; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C. | 0.401 |
| ADV68063.1 | glyA | Deima_2425 | Deima_2426 | COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR020843; KEGG: dge:Dgeo_0529 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SMART: Polyketide synthase, enoylreductase; SPTR: NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.540 |