STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADV68209.1Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018: IPR006674; KEGG: ddr:Deide_3p00240 putative metal dependent phosphohydrolase; PFAM: Diguanylate cyclase, predicted; GAF; Metal-dependent phosphohydrolase, HD subdomain; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Putative metal dependent phosphohydrolase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: HD domain; GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (899 aa)    
Predicted Functional Partners:
ADV66613.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR013656: IPR013767: IPR000160: IPR001633: IPR 000014; KEGG: dra:DR_0750 sensory box/GGDEF family protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold-4; PAS fold; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; SPTR: Sensory box/GGDEF family protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
 0.783
ADV67860.1
Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: hha:Hhal_0058 diguanylate phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; SMART: Diguanylate phosphodiesterase, EAL domain; SPTR: Diguanylate phosphodiesterase; PFAM: EAL domain.
  
    0.775
ADV68040.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterPro IPR013656: IPR000160: IPR001633: IPR000014; KEGG: dar:Daro_1052 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold-4; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.707
ADV67200.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633; KEGG: ddr:Deide_18060 putative diguanylate cyclase/phosphodiesterase; putative membrane protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Putative diguanylate cyclase/phosphodiesterase; putative membrane protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: d [...]
 
 
0.679
ADV68210.1
TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
       0.580
ADV68208.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: dge:Dgeo_1992 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; GAF; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; GAF; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.504
ADV66054.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160: IPR001633: IPR019734; KEGG: ddr:Deide_21850 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.503
ADV65939.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: ddr:Deide_2p00540 putative response regulator, CheY, putative response regulator PleD; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Putative response regulator, CheY, putative response regulator pleD; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
0.485
ADV67513.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR001440: IPR011717: IPR000160: IPR001633: IPR 019734; KEGG: ddr:Deide_03810 hypothetical protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF dom [...]
 
 
0.466
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
  
 
 0.464
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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