Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADV68441.1NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: dge:Dgeo_1510 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (226 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
    0.706
ADV68463.1
COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR022412: IPR002638: IPR004393; KEGG: ddr:Deide_13560 putative nicotinate-nucleotide diphosphorylase, carboxylating (nicotinate-nucleotide pyrophosphorylase, carboxylating)(quinolinate phosphoribosyltransferase, decarboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Putative Nicotinate-nucleotide diphosphorylase, carboxylating (Nicotinate-nucleotide pyrophosphorylase, carboxyl [...]
 
    0.682
ADV68440.1
4-alpha-glucanotransferase; COGs: COG3408 Glycogen debranching protein; InterPro IPR010401; KEGG: ddr:Deide_06370 putative glycogen debranching enzyme; PFAM: Amylo-alpha-1,6-glucosidase; PRIAM: 4-alpha-glucanotransferase; SPTR: Putative glycogen debranching enzyme; PFAM: Amylo-alpha-1,6-glucosidase; Glycogen debranching enzyme N terminal; TIGRFAM: glycogen debranching enzyme, archaeal type, putative.
       0.662
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
       0.556
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
Server load: low (12%) [HD]