Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADV68692.1Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001254; KEGG: dge:Dgeo_2025 peptidase S1 and S6, chymotrypsin/Hap; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Peptidase S1 and S6, chymotrypsin/Hap; PFAM: Trypsin. (356 aa)    
Predicted Functional Partners:
ADV68691.1
Uncharacterized protein family UPF0310; COGs: COG2947 conserved hypothetical protein; InterPro IPR002740; KEGG: dra:DR_0566 hypothetical protein; PFAM: Protein of unknown function DUF55; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF55.
       0.677
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.555
ADV68276.1
Peptidase M50; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915: IPR001478; KEGG: dra:DR_1507 hypothetical protein; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Putative zinc metalloprotease DR_1507; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.546
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
  
  
 0.536
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
   0.474
ADV66089.1
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR003661: IPR003594: IPR001789: IPR003018; KEGG: dge:Dgeo_2096 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; GAF; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: [...]
  
  
 0.468
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
   0.467
ADV66039.1
3-hydroxybutyryl-CoA epimerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: ddr:Deide_09650 putative peroxisomal bifunction; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA epimerase; SPTR: Putative Peroxisomal bifunction; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 
  0.460
rpsH
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
 
   0.453
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.434
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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