STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADV68710.1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (304 aa)    
Predicted Functional Partners:
ADV65668.1
COGs: COG0469 Pyruvate kinase; InterPro IPR001697: IPR015793: IPR015795; KEGG: dge:Dgeo_0005 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.975
ADV68708.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dra:DR_0623 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
 0.946
ADV66781.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302; KEGG: dge:Dgeo_2155 malate dehydrogenase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding; SPTR: Malate dehydrogenase (Oxaloacetate decarboxylating) (NADP+); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 0.934
ADV66159.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476; KEGG: dge:Dgeo_2339 transketolase, central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoisovalerate dehydrogenase, ODBB; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimid [...]
   
 0.919
ADV66750.1
COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476; KEGG: dge:Dgeo_1562 transketolase, central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 2-oxoisovalerate dehydrogenase, OdbB; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
   
 0.919
ADV65780.1
Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: noc:Noc_0471 thiamine pyrophosphate protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate oxidase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding [...]
  
 0.916
ADV66648.1
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.913
ADV65997.1
Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192: IPR008279: IPR000121: IPR010121; KEGG: chy:CHY_0443 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, [...]
  
 
 0.910
ADV66076.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: rmr:Rmar_1466 lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase.
   
 
 0.909
ADV66158.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: dge:Dgeo_2338 pyruvate dehydrogenase (lipoamide); PFAM: Dehydrogenase, E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: 2-oxoisovalerate dehydrogenase, OdbA; PFAM: Dehydrogenase E1 component.
   
 
 0.909
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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