STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV68830.1COGs: COG0248 Exopolyphosphatase; InterPro IPR003695: IPR006674; KEGG: ddr:Deide_01820 putative exopolyphosphatase, (ExopolyPase), (metaphosphatase), (Ppx/GppA phosphatase); PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD subdomain; PRIAM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; SPTR: Putative Exopolyphosphatase, (ExopolyPase), (Metaphosphatase), (Ppx/GppA phosphatase); PFAM: HD domain; Ppx/GppA phosphatase family. (498 aa)    
Predicted Functional Partners:
ADV67180.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.933
ADV68244.1
Polyphosphate:nucleotide phosphotransferase, PPK2 family; COGs: COG2326 conserved hypothetical protein; InterPro IPR022488: IPR022300; KEGG: dge:Dgeo_2247 hypothetical protein; PFAM: Polyphosphate kinase-2-related; SPTR: Predicted deoxynucleoside kinase; TIGRFAM: Polyphosphate:nucleotide phosphotransferase, PPK2; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:nucleotide phosphotransferase, PPK2 family.
 
  
 0.655
ADV68829.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR019734: IPR000160: IPR001633: IPR001440: IPR 011717; KEGG: ddr:Deide_21850 putative diguanylate-cyclase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Tetratricopeptide repeat; SPTR: Putative diguanylate-cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF [...]
     
 0.562
ADV68831.1
KEGG: dge:Dgeo_0273 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.523
ADV67862.1
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003018: IPR003661: IPR003594: IPR 001789; KEGG: ddr:Deide_2p01010 putative histidine kinase, hybrid; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction r [...]
     
 0.420
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.412
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.405
Your Current Organism:
Deinococcus maricopensis
NCBI taxonomy Id: 709986
Other names: D. maricopensis DSM 21211, Deinococcus maricopensis DSM 21211, Deinococcus maricopensis LB-34, Deinococcus maricopensis str. DSM 21211, Deinococcus maricopensis strain DSM 21211
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.