STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADY31771.1Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: clj:CLJU_c09370 branched-chain-amino-acid aminotransferase; PFAM: Aminotransferase, class IV; SPTR: Branched-chain-amino-acid aminotransferase; PFAM: Aminotransferase class IV. (261 aa)    
Predicted Functional Partners:
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404: IPR000581; KEGG: pdi:BDI_2073 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.975
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.972
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.909
ADY33244.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544: IPR005786; KEGG: pdi:BDI_1775 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain amino acid aminotransferase; TIGRFAM: Branched-chain amino acid aminotransferase II; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
     
  0.900
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.882
ADY31996.1
Aconitate hydratase domain-containing protein; COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR001030: IPR000573; KEGG: mka:MK1440 3-isopropylmalate dehydratase large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: 3-isopropylmalate dehydratase large subunit 1; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase).
  
  
 0.558
ADY32792.1
Pyruvate dehydrogenase (cytochrome); COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766; KEGG: pdi:BDI_0987 pyruvate dehydrogenase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; PRIAM: Pyruvate dehydrogenase (cytochrome); SPTR: Pyruvate dehydrogenase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 
 0.553
ADY33878.1
Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846: IPR012001: IPR012000: IPR011766; KEGG: zpr:ZPR_2802 acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzy [...]
  
 
 0.553
ADY31773.1
Domain of unknown function DUF2520-containing protein; COGs: COG5495 conserved hypothetical protein; InterPro IPR018931; KEGG: bfs:BF3122 hypothetical protein; PFAM: Domain of unknown function DUF2520; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF2520); NADP oxidoreductase coenzyme F420-dependent.
       0.550
ADY31772.1
Hypothetical protein; KEGG: tva:TVAG_365640 Dynein heavy chain family protein; SPTR: Terminase large subunit.
       0.544
Your Current Organism:
Odoribacter splanchnicus
NCBI taxonomy Id: 709991
Other names: O. splanchnicus DSM 20712, Odoribacter splanchnicus DSM 20712, Odoribacter splanchnicus str. DSM 20712, Odoribacter splanchnicus strain DSM 20712
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