Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFM16693.1Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase family. (363 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.802
AFM19801.1
Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase family.
  
     0.709
glnD
(protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
       0.628
AFM16334.1
PFAM: Response regulator receiver domain.
  
     0.551
AFM17797.1
Putative TIM-barrel fold metal-dependent hydrolase; PFAM: Amidohydrolase family.
 
     0.541
AFM16690.1
PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
       0.520
AFM17619.1
Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; formimidoylglutamase; Belongs to the arginase family.
  
  
 0.485
AFM19977.1
Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family.
  
  
 0.485
AFM17901.1
TIGR01777 family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: TIGR01777 family protein.
  
    0.433
AFM17968.1
TIGR01777 family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: TIGR01777 family protein.
  
    0.432
Your Current Organism:
Mycolicibacterium chubuense
NCBI taxonomy Id: 710421
Other names: M. chubuense NBB4, Mycobacterium chubuense NBB4, Mycolicibacterium chubuense NBB4
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