STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV73741.1Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family. (333 aa)    
Predicted Functional Partners:
cobB-2
NAD-dependent protein deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
 
  
 0.540
AEV72064.1
Transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family.
  
  
 0.525
AEV72141.1
PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.522
AEV73291.1
PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.519
AEV74396.1
DNA-binding domain-containing protein, AraC-type; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain.
 
 
 0.500
cobB
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.453
AEV74666.1
PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
   
  
 0.440
AEV73740.1
Hypothetical protein.
       0.422
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.411
AEV72524.1
PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
   
    0.408
Your Current Organism:
Mycolicibacterium rhodesiae NBB3
NCBI taxonomy Id: 710685
Other names: M. rhodesiae NBB3, Mycobacterium rhodesiae NBB3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.