STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU46600.1DNA methylase N-4/N-6 domain protein; COGs: COG0863 DNA modification methylase; InterPro IPR002941: IPR002052: IPR001091; KEGG: bph:Bphy_3423 DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase; Belongs to the N(4)/N(6)-methyltransferase family. (306 aa)    
Predicted Functional Partners:
ADU46601.1
KEGG: bph:Bphy_3423 DNA methylase N-4/N-6 domain-containing protein; SPTR: DNA methylase N-4/N-6 domain protein.
       0.773
ADU46599.1
ATPase associated with various cellular activities AAA_5; COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR011704: IPR003593; KEGG: cfl:Cfla_3299 ATPase associated with various cellular activities AAA_5; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: ATPase associated with various cellular activities AAA_5; manually curated; PFAM: AAA domain (dynein-related subfamily).
       0.633
ADU46602.1
Protein of unknown function DUF262; InterPro IPR004919; KEGG: ote:Oter_2248 hypothetical protein; PFAM: protein of unknown function DUF262; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF262.
  
  
 0.524
ADU46603.1
KEGG: npu:Npun_R0144 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.492
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
    0.480
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.405
ADU47609.1
Protein of unknown function DUF1116; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116).
   
    0.405
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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