STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nhaASodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (627 aa)    
Predicted Functional Partners:
ADU49484.1
Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR011017: IPR001757: IPR000695: IPR008250: IPR 005834: IPR007029: IPR006403: IPR006416: IPR018303; KEGG: nca:Noca_2922 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC [...]
 
 
 
 0.632
ADU46613.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.550
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.550
ADU47307.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...]
 
 
 
 0.529
ADU46611.1
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR012257: IPR017900: IPR017896; KEGG: gob:Gobs_0251 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
     
 0.525
ADU46612.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: sen:SACE_4261 (S)-2-hydroxy-acid oxidase, subunit D; PFAM: FAD linked oxidase domain protein; SPTR: (S)-2-hydroxy-acid oxidase, subunit D; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
       0.524
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.470
ADU49088.1
KEGG: scb:SCAB_33261 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.457
ADU47646.1
Hypothetical protein; KEGG: gob:Gobs_2142 40-residue YVTN family beta-propeller repeat protein; SPTR: 40-residue YVTN family beta-propeller repeat protein.
   
    0.435
ADU47680.1
COGs: COG4995 conserved hypothetical protein; KEGG: sro:Sros_3451 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.435
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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