STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU46613.1L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (604 aa)    
Predicted Functional Partners:
ADU46611.1
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR012257: IPR017900: IPR017896; KEGG: gob:Gobs_0251 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
  
  
 0.821
ADU46612.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: sen:SACE_4261 (S)-2-hydroxy-acid oxidase, subunit D; PFAM: FAD linked oxidase domain protein; SPTR: (S)-2-hydroxy-acid oxidase, subunit D; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
  
  
 0.806
ADU46614.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.665
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.568
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.552
nhaA
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
     
 0.546
ADU48563.1
(S)-2-hydroxy-acid oxidase; COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262: IPR012133: IPR008259; KEGG: sen:SACE_5887 L-lactate dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; PRIAM: (S)-2-hydroxy-acid oxidase; SPTR: L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.
  
  
 0.542
ADU50030.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133: IPR000262: IPR008259; KEGG: sen:SACE_6523 lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: Lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase.
  
  
 0.542
ADU47348.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.404
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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