Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU46626.1Cell elongation-specific peptidoglycan D,D-transpeptidase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: kse:Ksed_00200 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: PbpA; PFAM: Penicillin binding protein transpeptidase domain. (487 aa)    
Predicted Functional Partners:
ADU46627.1
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
 0.998
ADU47718.1
COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR003342: IPR018493: IPR018044; KEGG: tbi:Tbis_0672 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; glycosyl transferase family 39; SPTR: Probable penicillin-binding protein dacb1 (D-alanyl-d-alaninecarboxypeptidase) (Dd-peptidase) (Dd-carboxypeptidase); PFAM: D-alanyl-D-alanine carboxypeptidase; Dolichyl-phosphate-mannose-protein mannosyltransferase; Belongs to the peptidase S11 family.
 
 
 0.954
ADU47139.1
COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: kra:Krad_0527 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; SPTR: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.
     
 0.951
ADU48714.1
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tbi:Tbis_1685 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
  
  
 
0.922
ADU46629.1
COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: sco:SCO3844 secreted protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: Putative membrane protein; PFAM: FHA domain.
 
   
 0.907
ADU48032.1
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437: IPR018365: IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
 
 0.900
ADU48730.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018365: IPR001182; KEGG: fal:FRAAL1920 rod shape-determining membrane protein; cell elongation; PFAM: cell cycle protein; SPTR: Sfr protein; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.
 
 0.891
ADU46630.1
COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: kra:Krad_0077 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2662); FHA domain.
 
   
 0.885
ADU48035.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.885
ADU46628.1
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: kra:Krad_0075 protein phosphatase 2C-like; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Putative magnesium or manganese-dependent protein phosphatase; PFAM: Protein phosphatase 2C.
  
  
 0.881
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.