Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADU46632.1Peptidase S16 lon domain protein; COGs: COG2802 Uncharacterized protein similar to the N-terminal domain of Lon protease; InterPro IPR003111; KEGG: kra:Krad_3182 peptidase S16 lon domain protein; PFAM: peptidase S16 lon domain protein; SMART: peptidase S16 lon domain protein; SPTR: Peptidase S16 lon domain protein; PFAM: ATP-dependent protease La (LON) domain. (227 aa)    
Predicted Functional Partners:
ADU46798.1
Putative exonuclease; COGs: COG0419 ATPase involved in DNA repair; KEGG: cfl:Cfla_0124 putative exonuclease; SPTR: Putative exonuclease; TIGRFAM: exonuclease SbcC.
   
 0.501
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.468
ADU49053.1
KEGG: cms:CMS_1890 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.463
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
    
 0.463
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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