STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46635.1Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: sro:Sros_7934 putative LacI-family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Putative LacI-family transcriptional regulator; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family. (351 aa)    
Predicted Functional Partners:
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 
 0.865
ADU49742.1
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 
 
 0.601
ADU49653.1
Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: nca:Noca_0101 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
  
 0.589
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.579
ADU46636.1
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pak:HMPREF0675_5030 bacterial extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein.
     
 0.569
xylB
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterProIPR018484: IPR018485: IPR006000: IPR019825: IPR 018483; KEGG: svi:Svir_04580 D-xylulose kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.
 
 
 
 0.567
ADU46634.1
Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: chy:CHY_0890 alpha/beta fold family hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Lysophospholipase L2; PFAM: Putative lysophospholipase.
       0.502
ADU46638.1
Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pak:HMPREF0675_5028 ABC transporter, permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport permease; PFAM: Binding-protein-dependent transport system inner membrane component.
 
   
 0.483
ADU49654.1
ABC transporter related protein; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nca:Noca_0100 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter.
 
  
 0.454
ADU48859.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: ace:Acel_1852 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
 
   0.449
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.