Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU46653.1beta-Ig-H3/fasciclin; COGs: COG2335 Secreted and surface protein containing fasciclin-like repeats; InterPro IPR000782: IPR017909; KEGG: nca:Noca_4534 beta-Ig-H3/fasciclin; PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; SPTR: Beta-Ig-H3/fasciclin; PFAM: Fasciclin domain. (213 aa)    
Predicted Functional Partners:
ADU46652.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: nca:Noca_4535 RNA polymerase sigma factor SigK; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
 
  
 0.826
ADU46651.1
Anti-sigma K factor RskA; InterPro IPR018764; KEGG: nca:Noca_4536 hypothetical protein; PFAM: Anti-sigma K factor RskA; SPTR: Putative uncharacterized protein; PFAM: Anti-sigma-K factor rskA.
 
   
 0.825
nuoD
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
    
   0.802
nuoD-2
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
    
   0.802
ADU46654.1
Oxidoreductase molybdopterin binding protein; COGs: COG2041 Sulfite oxidase; InterPro IPR000572: IPR005066: IPR006311; KEGG: nca:Noca_4533 oxidoreductase, molybdopterin binding; PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; SPTR: Oxidoreductase, molybdopterin binding; PFAM: Mo-co oxidoreductase dimerisation domain; Oxidoreductase molybdopterin binding domain.
 
     0.736
ADU46712.1
Protein of unknown function DUF1365; COGs: COG3496 conserved hypothetical protein; InterPro IPR010775; KEGG: rer:RER_23220 hypothetical protein; PFAM: protein of unknown function DUF1365; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1365).
 
  
 0.579
ADU46713.1
Amine oxidase; COGs: COG2907 NAD/FAD-binding protein; InterPro IPR002937; KEGG: sgr:SGR_5877 putative amine oxidoreductase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase.
 
   
 0.500
ADU46709.1
COGs: COG0415 Deoxyribodipyrimidine photolyase; InterProIPR006050: IPR005101: IPR001969: IPR018394: IPR 002081; KEGG: kra:Krad_3554 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: Phr; PFAM: FAD binding domain of DNA photolyase; DNA photolyase.
 
  
 0.489
ADU46655.1
KEGG: sco:SCO6177 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
       0.440
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.403
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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