STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU46689.1COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR007887: IPR001460: IPR002137; KEGG: nca:Noca_4600 penicillin-binding protein, transpeptidase; PFAM: penicillin-binding protein transpeptidase; NTF2 domain protein transpeptidase; SPTR: Penicillin-binding protein, transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; NTF2-like N-terminal transpeptidase domain; Penicillin-binding Protein dimerisation domain. (644 aa)    
Predicted Functional Partners:
ADU48035.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.857
ADU47458.1
Septum formation initiator; InterPro IPR007060; KEGG: kra:Krad_1074 septum formation initiator; PFAM: Septum formation initiator; SPTR: Septum formation initiator; PFAM: Septum formation initiator.
 
 
 0.693
ADU50092.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kra:Krad_4341 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative secreted penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
   
 
 0.670
ADU47016.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kse:Ksed_25450 membrane carboxypeptidase (penicillin-binding protein); PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
 
 
 
 0.659
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.658
ADU48032.1
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437: IPR018365: IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.640
ADU48730.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018365: IPR001182; KEGG: fal:FRAAL1920 rod shape-determining membrane protein; cell elongation; PFAM: cell cycle protein; SPTR: Sfr protein; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.
 
 
 0.637
ADU46627.1
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
  
 
 0.587
ADU47139.1
COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: kra:Krad_0527 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; SPTR: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.
  
   
 0.560
ADU46690.1
Protein of unknown function DUF2183; COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: kfl:Kfla_5428 hypothetical protein; PFAM: Protein of unknown function DUF2183; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2183).
       0.559
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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