STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46692.1COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749: IPR004625; KEGG: nca:Noca_4006 pyridoxamine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Pyridoxal kinase; SPTR: Pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase; Belongs to the pyridoxine kinase family. (285 aa)    
Predicted Functional Partners:
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
 
  
 0.929
pdxT
Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.918
pdxS
Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 0.916
ADU48038.1
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.661
ADU46691.1
DNA-(apurinic or apyrimidinic site) lyase; COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319: IPR015886: IPR000214; KEGG: sna:Snas_1400 DNA-formamidopyrimidine glycosylase; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Putative formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg); Belongs to the FPG family.
       0.625
ADU48813.1
Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; COGs: COG3576 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; InterPro IPR011576; KEGG: azl:AZL_002750 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: Pyridoxamine 5'-phosphate oxidase.
  
  
  0.625
ADU46690.1
Protein of unknown function DUF2183; COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: kfl:Kfla_5428 hypothetical protein; PFAM: Protein of unknown function DUF2183; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2183).
 
     0.484
ADU47439.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: kse:Ksed_03410 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding subunit; PFAM: ABC transporter.
     
 0.435
ADU46693.1
Hypothetical protein; InterPro IPR005829: IPR009056; KEGG: kse:Ksed_01160 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.430
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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