Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADU46707.1TspO/MBR family protein; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR004307; KEGG: krh:KRH_21230 hypothetical protein; PFAM: TspO/MBR family protein; NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; PFAM: TspO/MBR family; NmrA-like family. (491 aa)    
Predicted Functional Partners:
ADU46709.1
COGs: COG0415 Deoxyribodipyrimidine photolyase; InterProIPR006050: IPR005101: IPR001969: IPR018394: IPR 002081; KEGG: kra:Krad_3554 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: Phr; PFAM: FAD binding domain of DNA photolyase; DNA photolyase.
 
  
 0.962
ADU46997.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase.
  
 
 0.904
ADU48495.1
Menaquinol-cytochrome c reductase iron-sulfur subunit precursor; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: kse:Ksed_16200 Rieske Fe-S protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulphur component of ubiQ-cytB reductase; PFAM: Rieske [2Fe-2S] domain.
  
 
 0.888
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 0.868
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 0.862
nuoI-2
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 0.862
ADU46708.1
Abortive infection protein; InterPro IPR003675; KEGG: kse:Ksed_01050 CAAX amino terminal protease family; PFAM: Abortive infection protein; SPTR: Probable integral membrane protein; PFAM: CAAX amino terminal protease family.
 
     0.845
ADU46712.1
Protein of unknown function DUF1365; COGs: COG3496 conserved hypothetical protein; InterPro IPR010775; KEGG: rer:RER_23220 hypothetical protein; PFAM: protein of unknown function DUF1365; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1365).
       0.841
ADU46713.1
Amine oxidase; COGs: COG2907 NAD/FAD-binding protein; InterPro IPR002937; KEGG: sgr:SGR_5877 putative amine oxidoreductase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase.
       0.841
ADU46710.1
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR002347; KEGG: avi:Avi_0085 gluconate 5-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.822
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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