STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46715.1Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR006158; KEGG: msv:Mesil_1484 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Probable transcriptional regulator; PFAM: MerR family regulatory protein; B12 binding domain. (304 aa)    
Predicted Functional Partners:
ADU46714.1
Polyketide cyclase/dehydrase; InterPro IPR019587; KEGG: art:Arth_3265 hypothetical protein; PFAM: Polyketide cyclase/dehydrase; SPTR: Putative uncharacterized protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
 
     0.764
ADU46707.1
TspO/MBR family protein; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR004307; KEGG: krh:KRH_21230 hypothetical protein; PFAM: TspO/MBR family protein; NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; PFAM: TspO/MBR family; NmrA-like family.
 
  
 0.757
ADU47740.1
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
   
 
 0.754
ADU46709.1
COGs: COG0415 Deoxyribodipyrimidine photolyase; InterProIPR006050: IPR005101: IPR001969: IPR018394: IPR 002081; KEGG: kra:Krad_3554 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: Phr; PFAM: FAD binding domain of DNA photolyase; DNA photolyase.
 
  
 0.714
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
   
 
 0.589
ADU46712.1
Protein of unknown function DUF1365; COGs: COG3496 conserved hypothetical protein; InterPro IPR010775; KEGG: rer:RER_23220 hypothetical protein; PFAM: protein of unknown function DUF1365; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1365).
     
 0.559
ADU46713.1
Amine oxidase; COGs: COG2907 NAD/FAD-binding protein; InterPro IPR002937; KEGG: sgr:SGR_5877 putative amine oxidoreductase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase.
       0.550
ADU46708.1
Abortive infection protein; InterPro IPR003675; KEGG: kse:Ksed_01050 CAAX amino terminal protease family; PFAM: Abortive infection protein; SPTR: Probable integral membrane protein; PFAM: CAAX amino terminal protease family.
 
     0.542
ADU46711.1
COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR003333; KEGG: sen:SACE_6753 cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; PRIAM: Cyclopropane-fatty-acyl-phospholipid synthase; SPTR: Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (Cyclopropane fatty acid synthase) (CFA synthase); PFAM: Cyclopropane-fatty-acyl-phospholipid synthase.
     
 0.539
ADU48268.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.527
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.