STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46738.1KEGG: xce:Xcel_3194 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain. (185 aa)    
Predicted Functional Partners:
ADU46739.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: cfl:Cfla_0574 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
    0.783
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.602
ADU46698.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Car [...]
  
 
 0.594
ADU46737.1
Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: xce:Xcel_3229 diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: Putative uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain.
       0.563
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.551
nuoI-2
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.551
ADU48457.1
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: gob:Gobs_3234 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family.
  
  
 0.535
ADU49412.1
KEGG: bcv:Bcav_1237 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.535
nuoD
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.497
nuoD-2
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.497
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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