STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46750.12-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: kfl:Kfla_1685 myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Putative myo-inositol catabolism protein; PFAM: Xylose isomerase-like TIM barrel. (317 aa)    
Predicted Functional Partners:
ADU46966.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.799
ADU46642.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.786
ADU46739.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: cfl:Cfla_0574 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
  
 0.635
ADU47775.1
Oxidoreductase domain-containing protein; COGs: COG0673 dehydrogenase and related protein; KEGG: net:Neut_1547 oxidoreductase domain-containing protein; SPTR: Oxidoreductase domain protein.
  
  
 0.635
ADU48532.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: ske:Sked_15440 predicted dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Putative oxidoreductase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
  
 0.635
ADU48271.1
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590: IPR010061; KEGG: msv:Mesil_1872 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
 
  
 0.585
ADU46749.1
Pyridine nucleotide-disulfide oxidoreductase dimerization region; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR001327: IPR004099: IPR013027: IPR000815; KEGG: sco:SCO3443 pyridine nucleotide-disulphide oxidoreductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
       0.578
ADU47684.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sen:SACE_1230 sugar kinase, phosphofructokinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, possible phosphofructokinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.568
ADU46751.1
KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated.
       0.566
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.550
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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