Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU46750.12-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: kfl:Kfla_1685 myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Putative myo-inositol catabolism protein; PFAM: Xylose isomerase-like TIM barrel. (317 aa)    
Predicted Functional Partners:
ADU46966.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.729
ADU46642.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.712
ADU46749.1
Pyridine nucleotide-disulfide oxidoreductase dimerization region; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR001327: IPR004099: IPR013027: IPR000815; KEGG: sco:SCO3443 pyridine nucleotide-disulphide oxidoreductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
     
 0.588
ADU46751.1
KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated.
       0.567
ADU46967.1
Glycoside hydrolase family 4; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: sgr:SGR_1058 putative 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Putative 6-phospho-beta-glucosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain.
  
     0.542
ADU46965.1
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: kfl:Kfla_5626 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein.
 
  
 0.540
ADU48271.1
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590: IPR010061; KEGG: msv:Mesil_1872 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
 
  
 0.516
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
       0.425
ADU49653.1
Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: nca:Noca_0101 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
  
 0.422
ADU47684.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sen:SACE_1230 sugar kinase, phosphofructokinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, possible phosphofructokinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.417
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.