STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46759.1Isochorismatase hydrolase; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: sna:Snas_0489 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family. (186 aa)    
Predicted Functional Partners:
ADU49645.1
Isochorismatase hydrolase; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: nca:Noca_0201 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family.
  
     0.704
ADU46760.1
tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537; KEGG: kse:Ksed_01710 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: Putative rRNA methylase; PFAM: SpoU rRNA Methylase family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.543
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
   
    0.478
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.444
ADU46761.1
KEGG: kse:Ksed_01720 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.443
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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