STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46765.1KEGG: sro:Sros_0019 hypothetical protein; SPTR: Putative uncharacterized protein. (313 aa)    
Predicted Functional Partners:
ADU46766.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR006403: IPR 006416: IPR001757: IPR018303: IPR017969: IPR000150: IPR000695; KEGG: rop:ROP_pROB01-02380 putative copper-transporting ATPase CopA; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative copper-transporting ATPase CopA; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, su [...]
   
 0.897
ADU46764.1
InterPro IPR006121: IPR017969: IPR000428; KEGG: amd:AMED_3508 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Putative metal-binding protein; PFAM: Heavy-metal-associated domain.
 
 
 
 0.885
ADU47307.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...]
  
 
 0.516
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
  
 0.503
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
 
    0.496
ADU49484.1
Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR011017: IPR001757: IPR000695: IPR008250: IPR 005834: IPR007029: IPR006403: IPR006416: IPR018303; KEGG: nca:Noca_2922 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC [...]
    
 0.470
ADU46582.1
KEGG: mmi:MMAR_4843 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.468
ADU46751.1
KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated.
 
    0.459
ADU49336.1
KEGG: bcv:Bcav_1591 glycoside hydrolase family 2 sugar binding; SPTR: Glycoside hydrolase family 2 sugar binding; PFAM: Protein of unknown function (DUF2804).
 
 
 
 0.451
ADU49308.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000595: IPR003594: IPR005467: IPR004358; KEGG: rha:RHA1_ro04003 sensor kinase, two-component system; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
   0.438
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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