STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46773.1Peptidase M48 Ste24p; InterPro IPR001915; KEGG: msm:MSMEG_3631 integral membrane protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48. (298 aa)    
Predicted Functional Partners:
ADU46774.1
Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: kse:Ksed_01860 predicted transcriptional regulator; PFAM: Penicillinase repressor; SPTR: Transcriptional regulator-like protein; PFAM: Penicillinase repressor.
 
    0.962
ADU46777.1
COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: nca:Noca_0943 cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: Cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB).
       0.806
ADU46776.1
ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; COGs: COG4988 ABC-type transport system involved in cytochrome bd biosynthesis ATPase and permease components; InterProIPR001140: IPR003439: IPR014216: IPR003593: IPR 017871: IPR017940; KEGG: kse:Ksed_01870 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: Putative ABC transporter; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-bi [...]
       0.790
ADU46778.1
COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: nca:Noca_0942 cytochrome bd ubiquinol oxidase, subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: Cytochrome d ubiquinol oxidase subunit I; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
       0.788
ADU46775.1
ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; COGs: COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase and permease components; InterPro IPR003439: IPR014223: IPR003593: IPR017940; KEGG: kse:Ksed_01870 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative ABC transporter ATP-binding protein; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC tran [...]
       0.782
ADU49428.1
Protein of unknown function DUF2596; InterPro IPR019706; KEGG: sgr:SGR_3994 hypothetical protein; PFAM: Protein of unknown function DUF2596; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2596).
  
     0.570
ADU46779.1
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family.
     
 0.515
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.504
ADU46857.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR017900: IPR017896; KEGG: kse:Ksed_26190 Fe-S oxidoreductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative iron-sulphur-binding reductase; PFAM: Cysteine-rich domain.
 
   
 0.459
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 
 0.449
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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